The group EPISTEME studies technical and scientific texts from classical antiquity to the early modern period. It mainly focuses on the development of the classical medical tradition up to the authors of the seventeenth century, especially if connected to Portuguese culture. The research group is also involved in the diachronic study of medical technical terminology, which ultimately traces back to the Greek tradition and its canonical authors as well as to the evidence of paraliterary and documentary papyri of medical content. The group also examines the interaction between the classical education prevalent in Europe until the eighteenth century and the dynamics of knowledge preservation, transmission, and creation, and is interested in how theory intermingles with practice. The overall goal is to contribute to a more accurate picture of the historical development of scientific culture in Portugal and in Europe.